Researchers' breakthrough in treatment of deadly peanut allergies in children

Barsaba Taglieri
Agosto 17, 2017

In a medical breakthrough, Australian researchers have successfully found treatment for deadly peanut allergies. "These findings suggest our treatment is effective at inducing long-term tolerance, up to four years after completing treatment, and is safe".

Prof Tang said the new study showed that the majority of PPOIT-treated children who tolerated peanut at the end of the original trial were still eating peanut without reactions four years later.

A small clinical trial conducted at Murdoch Children's Research Institute helped two-thirds of children rid of their allergy to peanuts through experimental immunotherapy.

She went on to explain that the study results hope to change the lives of children with peanut allergies and maybe all food allergies.

Professor Mimi Tang, from Murdoch Children's Research Institute, said they found 70 per cent of children were able to stomach peanuts without suffering any reactions.

'We had children who came into the study allergic to peanuts, having to avoid peanuts in their diet, being very vigilant around that, carrying a lot of anxiety, ' she said.

"For the first time, we could have products on the market that provide meaningful and long lasting treatment benefits, which allow sufferers to eat peanut products without thinking about it, as part of a regular diet", said ProTA Therapeutics CEO, Dr Suzanne Lipe.

About one per cent of the world's population has a peanut allergy, but it is one of the most severe food allergies and the most common cause of anaphylaxis, which is a life-threatening allergic reaction.

Instead of avoiding peanuts, the treatment is created to reset the way the immune system responds to peanuts so it no longer produces an allergic reaction.

A total of 48 children were enrolled in the PPOIT trial and were randomly given either a combination of the probiotic, Lactobacillus rhamnosus, together with peanut protein in increasing amounts, or a placebo, once daily for 18 months.

Researchers are now aiming to confirm the results with a larger study of the treatment they say "holds important implications for attacking the modern food allergy epidemic".

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